Description

n-(3-Ethoxypropyl)-4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is a high-value, advanced pharmaceutical intermediate featuring a protected boronic ester functional group. This compound matters for its critical role as a key building block in modern cross-coupling reactions, enabling the efficient synthesis of complex molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: As a versatile boronic ester reagent for constructing biaryl and heterobiaryl structures in drug discovery.
• Pharmaceutical Intermediate: For the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Agrochemical Research: In the development of novel herbicides, fungicides, and insecticides requiring specific pyridine-based scaffolds.
• Material Science: As a monomer or precursor for creating organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology: For synthesizing probes and tool compounds used in biochemical and cellular assays.
• Process Chemistry & Scale-up: Used in optimizing synthetic routes from laboratory to pilot and commercial scale production.

Basic Information

Product Name	n-(3-Ethoxypropyl)-4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine
CAS No.	1351995-07-7
Molecular Formula	C17H29BN2O3
Molecular Weight	320.24 g/mol
Synonyms	4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(3-ethoxypropyl)pyridin-2-amine; 2-Amino-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine N-(3-ethoxypropyl) derivative; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-methyl-N-(3-ethoxypropyl)pyridin-2-amine; Pinacol ester of [5-Amino-6-((3-ethoxypropyl)amino)-3-methylpyridin-2-yl]boronic acid; Boric acid, B-[5-amino-6-[(3-ethoxypropyl)amino]-3-methyl-2-pyridinyl]-, 2,2-dimethyl-1,3-propanediyl ester
EINECS	Contact for details

Quality Control

Our n-(3-Ethoxypropyl)-4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and consistent performance for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.