Description

N1,N1-Dimethyl-N2-(4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Ethane-1,2-Diamine is a high-value, advanced pharmaceutical intermediate featuring a pyridine core and a protected boronic ester functional group. This compound is critical for facilitating efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are foundational to modern medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling Reagent: The pinacol boronate ester moiety enables efficient carbon-carbon bond formation with aryl/heteroaryl halides, a cornerstone of modern organic synthesis.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to optimize drug-like properties and potency.
• Ligand Synthesis: The diamine structure can be utilized to develop novel ligands for catalysis or metal-organic frameworks (MOFs).
• Agrochemical Development: Potential application as an intermediate in the synthesis of advanced crop protection agents.
• Material Science Precursor: Can be incorporated into organic electronic materials or polymers requiring specific boron-nitrogen functionalities.

Basic Information

Product Name	N1,N1-Dimethyl-N2-(4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Ethane-1,2-Diamine
CAS No.	1351995-04-4
Molecular Formula	C18H32BN3O2
Molecular Weight	333.28 g/mol
Synonyms	2-[(2-Dimethylaminoethyl)amino]-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-[(2-(dimethylamino)ethyl)amino]-4-methylpyridine; N,N-Dimethyl-N'-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-methyl-2-pyridinyl]-1,2-ethanediamine; 1351995-04-4; Boronic acid, B-[2-[[2-(dimethylamino)ethyl]amino]-4-methyl-5-pyridinyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Our production of N1,N1-Dimethyl-N2-(4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Ethane-1,2-Diamine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and LC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.