Description

4-Chloro-2-Fluoro-3-Methylbenzaldehyde is a high-purity, multi-functional aromatic aldehyde building block essential for advanced organic synthesis. Its unique halogenated and substituted benzaldehyde structure makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the chloro-fluoro-methyl substitution pattern can enhance biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and advanced polymers where specific halogen interactions are required.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-Chloro-2-Fluoro-3-Methylbenzaldehyde
CAS No.	1351668-29-5
Molecular Formula	C8H6ClFO
Molecular Weight	172.58 g/mol
Synonyms	3-Methyl-4-chloro-2-fluorobenzaldehyde; 2-Fluoro-3-methyl-4-chlorobenzaldehyde; 4-Chloro-2-fluoro-m-tolualdehyde; Benzaldehyde, 4-chloro-2-fluoro-3-methyl-; 1351668-29-5
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Fluoro-3-Methylbenzaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP starting materials and ensures reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening containers for use. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<10 ppm
Residue on Ignition	<0.1%
Water Content (KF)	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.