Description

n-Cyclopropyl-2-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide is a high-purity boronic ester derivative, a critical intermediate in modern synthetic organic chemistry. Its value lies in enabling efficient and selective cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and fungicides.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Suzuki-Miyaura Cross-Coupling: The primary application is as a boronic ester coupling partner for forming carbon-carbon bonds under mild conditions.
• Chemical Biology Probes: Utilized in the development of molecular probes and bioconjugation reagents for diagnostic and research applications.
• Academic & Industrial R&D: A valuable reagent for synthetic methodology development and library synthesis in medicinal chemistry.

Basic Information

Product Name	n-Cyclopropyl-2-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide
CAS No.	1351374-48-5
Molecular Formula	C18H26BNO3
Molecular Weight	315.22 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-cyclopropyl-2-methylbenzamide; 2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-cyclopropylbenzamide; Benzamide, N-cyclopropyl-2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Pinacol ester of [2-Methyl-4-(N-cyclopropylcarbamoyl)phenyl]boronic acid
EINECS	Contact for details

Quality Control

Our n-Cyclopropyl-2-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed under an inert atmosphere to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.