Description

N,n-Diethyl-4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is a high-value, advanced pharmaceutical intermediate and building block featuring a pinacol boronate ester group. This compound matters for its critical role in modern synthetic chemistry, particularly in Suzuki-Miyaura cross-coupling reactions, which are fundamental for constructing complex molecules in drug discovery and materials science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to introduce functionalized pyridine motifs into target structures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing complex heterocyclic systems.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds between the boronate ester and various aryl/heteroaryl halides, a cornerstone reaction in medicinal chemistry.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific pyridine-based architectures.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology & Proteomics: Can be utilized in the development of molecular probes and bioconjugation tools due to its reactive boronate handle.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis organizations (CSOs) and CDMOs producing bespoke organic compounds for client projects.

Basic Information

Product Name	N,n-Diethyl-4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine
CAS No.	1351206-51-3
Molecular Formula	C16H27BN2O2
Molecular Weight	290.21 g/mol
Synonyms	2-Amino-N,N-diethyl-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-diethyl-4-methylpyridin-2-amine; N,N-Diethyl-4-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine; 1351206-51-3; Boronic acid, B-[2-(diethylamino)-6-methyl-4-pyridinyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester; Pinacol [2-(diethylamino)-6-methyl-4-pyridinyl]boronate
EINECS	Contact for details

Quality Control

Our N,n-Diethyl-4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for advanced intermediates, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.