Description

2-Amino-1,5-anhydro-2,4-dideoxy-D-threo-pentitol is a specialized amino sugar derivative and a key chiral building block in advanced organic synthesis. This high-purity intermediate is critical for researchers and manufacturers requiring precise stereochemistry for complex molecule construction. It is primarily utilized in the pharmaceutical and biotechnology sectors for the development of novel therapeutics, including nucleoside analogs and carbohydrate-based drugs.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the research and production of antiviral and anticancer nucleoside analogs.
• Glycobiology Research: Used in the synthesis of modified sugars and glycomimetics for studying carbohydrate-protein interactions and metabolic pathways.
• Bioconjugation Chemistry: Acts as a linker or functional handle for attaching payloads in antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Probes: Employed in the development of activity-based probes and inhibitors targeting glycosidases or glycosyltransferases.
• Process Chemistry: Utilized in scale-up and optimization for the commercial manufacturing of active pharmaceutical ingredients (APIs).
• Academic & Industrial R&D: A valuable reagent for synthetic methodology development and exploring new chemical space in medicinal chemistry.

Basic Information

Product Name	2-Amino-1,5-anhydro-2,4-dideoxy-D-threo-pentitol
CAS No.	1350734-61-0
Molecular Formula	C5H11NO3
Molecular Weight	133.15 g/mol
Synonyms	1,5-Anhydro-2-amino-2,4-dideoxy-D-threo-pentitol; 2-Amino-1,5-anhydro-2,4-dideoxy-D-threo-pentitol; D-threo-2-Amino-1,5-anhydro-2,4-dideoxypentitol; Amino-deoxy-anhydropentitol derivative; CAS 1350734-61-0; AADP; 2-AADP
EINECS	Contact for details

Quality Control

Our 2-Amino-1,5-anhydro-2,4-dideoxy-D-threo-pentitol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.