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4-Methyl-2-(Piperidin-3-Yloxy)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine CAS NO 1350559-15-7


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CAS No.:1350559-15-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Methyl-2-(Piperidin-3-Yloxy)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, multi-functional chemical intermediate featuring a protected boronic acid ester (pinacol boronate) group. This compound is essential for modern synthetic chemistry, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction, enabling the efficient construction of complex molecular architectures. It is primarily sought after by pharmaceutical R&D teams, agrochemical innovators, and advanced material scientists for the synthesis of novel active ingredients and functional molecules.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for kinase inhibitors and other small-molecule therapeutics.
  • Agrochemical Research: Used in creating novel active ingredients for crop protection products, leveraging its boronate functionality for structural diversification.
  • Material Science: Serves as a precursor in the development of organic electronic materials, such as those used in OLEDs and organic photovoltaics.
  • Chemical Synthesis: A versatile reagent for Suzuki-Miyaura cross-coupling reactions to form biaryl and heterobiaryl linkages.
  • Ligand & Catalyst Development: Employed in the research and synthesis of novel ligands and organometallic catalysts.
  • Life Sciences & Diagnostics: Potential use in developing molecular probes and imaging agents for biochemical research.

Basic Information

Product Name 4-Methyl-2-(Piperidin-3-Yloxy)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No. 1350559-15-7
Molecular Formula C18H29BN2O3
Molecular Weight 332.25 g/mol
Synonyms 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-((3-piperidyl)oxy)-4-picoline; 2-((Piperidin-3-yl)oxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-methylpyridine; 4-Methyl-2-(3-piperidyloxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 1350559-15-7; Boronic acid, B-[2-[(3-piperidinyl)oxy]-4-methyl-5-pyridinyl]-, 1,3,2-dioxaborolane deriv.
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Quality Control

Our production of 4-Methyl-2-(Piperidin-3-Yloxy)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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