Description

1-Ethyl-6-Oxo-1,6-Dihydropyridine-3-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its core value lies in its protected boronic acid functionality, which is essential for critical carbon-carbon bond-forming reactions like the Suzuki-Miyaura cross-coupling. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing complex pyridine and dihydropyridine cores.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a crucial organoboron reagent for palladium-catalyzed coupling with aryl/heteroaryl halides, enabling efficient library synthesis for drug discovery.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific heterocyclic structures.
• Material Science & OLED Development: Acts as a precursor for creating organic electronic materials, ligands for catalysts, and light-emitting compounds.
• Chemical Biology & Probe Development: Utilized in the design and synthesis of molecular probes and bio-conjugates for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, high-value boronic ester derivatives.

Basic Information

Product Name	1-Ethyl-6-Oxo-1,6-Dihydropyridine-3-Boronic Acid Pinacol Ester
CAS No.	1349734-00-4
Molecular Formula	C13H20BNO3
Molecular Weight	249.12 g/mol
Synonyms	(1-Ethyl-6-oxo-1,6-dihydropyridin-3-yl)boronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-ethylpyridin-2(1H)-one; 1-Ethyl-2-oxo-1,2-dihydropyridine-5-boronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-ethyl-2(1H)-pyridinone; 1-Ethyl-6-oxo-1,6-dihydropyridine-3-boronic acid, pinacol ester; Boronic acid, B-(1-ethyl-6-oxo-1,6-dihydro-3-pyridinyl)-, pinacol ester
EINECS	Contact for details

Quality Control

Our 1-Ethyl-6-Oxo-1,6-Dihydropyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive coupling reactions. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the stringent requirements of pharmaceutical R&D and scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon/nitrogen) when possible to maintain stability and prevent hydrolysis of the boronic ester group. Keep container tightly sealed in a desiccated environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.