Description

Benzoic Acid, 4-Formyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Methyl Ester is a high-value, multifunctional chemical building block that integrates a formyl group and a boronic ester pinacol ester moiety on a benzoate scaffold. This unique structure makes it a critical intermediate for advanced organic synthesis, particularly in cross-coupling reactions. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecules. The compound, with CAS number 1349171-53-4, enables precise molecular architecture essential for modern drug discovery and material science.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific aryl-boronate functionalities.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create tagged molecules and probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses serving the biotechnology and fine chemical industries.

Basic Information

Item	Detail
Product Name	Benzoic Acid, 4-Formyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Methyl Ester
CAS No.	1349171-53-4
Molecular Formula	C15H19BO5
Molecular Weight	290.12 g/mol
Synonyms	Methyl 4-formyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate; 3-Borono-4-formylbenzoic Acid Methyl Ester, Pinacol Ester; 2-Methoxycarbonyl-5-formylphenylboronic Acid Pinacol Ester; Methyl 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-formylbenzoate; (4-Formyl-3-(methoxycarbonyl)phenyl)boronic Acid Pinacol Ester; 4-Formyl-3-methoxycarbonylbenzeneboronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 4-Formyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Methyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our quality commitment supports applications in GMP-related synthesis and other regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.