Description

1-Isopropyl-6-Oxo-1,6-Dihydropyridine-3-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate belonging to the class of protected boronic acid derivatives. This compound is a critical building block in modern organic synthesis, valued for its stability and reactivity in cross-coupling reactions. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex biaryl and heterobiaryl structures.
• Pharmaceutical Intermediate: Serves as a crucial building block in the research and production of potential drug candidates, particularly in kinase inhibitor and antiviral agent development.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers.
• Chemical Biology Probes: Facilitates the development of molecular probes for studying biological processes and target identification.
• Process Chemistry & Scale-up: Provides a reliable and scalable intermediate for transitioning from laboratory-scale discovery to commercial manufacturing.

Basic Information

Product Name	1-Isopropyl-6-Oxo-1,6-Dihydropyridine-3-Boronic Acid Pinacol Ester
CAS No.	1349151-98-9
Molecular Formula	C14H22BNO3
Molecular Weight	263.14 g/mol
Synonyms	1-Isopropyl-6-oxo-1,6-dihydropyridine-3-boronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-isopropylpyridin-2(1H)-one; 1-Isopropyl-2-oxo-1,2-dihydropyridine-5-boronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-isopropylpyridin-2(1H)-one; 1-Isopropyl-6-oxo-1,6-dihydro-3-pyridineboronic acid pinacol ester; Boronic acid, B-(1-isopropyl-6-oxo-1,6-dihydro-3-pyridinyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 1-Isopropyl-6-Oxo-1,6-Dihydropyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided to guarantee consistency and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.