Description

n-Cyclopentyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine is a high-value, functionalized pyridine boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to develop novel active ingredients and functional molecules. The protected boronate ester group offers enhanced stability and handling characteristics compared to the free boronic acid.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used to create novel herbicides, fungicides, and insecticides by constructing complex heterocyclic cores.
• Material Science: Building block for organic electronic materials, such as ligands for OLEDs and charge-transport materials.
• Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): Enables the modular construction of bifunctional molecules for targeted protein degradation.
• Ligand Synthesis: Intermediate for preparing sophisticated chiral and achiral ligands used in catalysis.
• Library Synthesis for Drug Discovery: Enables high-throughput parallel synthesis to generate diverse compound libraries for screening.

Basic Information

Product Name	n-Cyclopentyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine
CAS No.	1346808-54-5
Molecular Formula	C16H25BN2O2
Molecular Weight	288.20 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-cyclopentylpyridin-2-amine; 2-Pyridinamine, N-cyclopentyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; n-Cyclopentyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinamine; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(cyclopentylamino)pyridine; BCPY Boronate Ester; Cyclopentyl-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)amine
EINECS	Contact for details

Quality Control

Our n-Cyclopentyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.