Description

2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1,3,4-Oxadiazole is a high-value organoboron building block, specifically a boronic ester derivative of a 1,3,4-oxadiazole heterocycle. This compound is essential for facilitating efficient carbon-carbon and carbon-heteroatom bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of modern synthetic chemistry. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for introducing the 1,3,4-oxadiazole pharmacophore into drug candidates, which is associated with a wide range of biological activities including antimicrobial, anti-inflammatory, and anticancer properties.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the oxadiazole ring contributes to product efficacy and stability.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge-transport layers, due to its electron-deficient heterocyclic core.
• Ligand and Catalyst Development: Employed in the synthesis of novel bidentate or polydentate ligands for metal catalysis, leveraging the nitrogen atoms of the oxadiazole ring.
• Chemical Biology Probes: Utilized in the construction of bioconjugates and activity-based probes for studying biological processes and target identification.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with tailored thermal and electronic properties.

Basic Information

Item	Details
Product Name	2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1,3,4-Oxadiazole
CAS No.	1346808-32-9
Molecular Formula	C8H13BN2O3
Molecular Weight	196.02 g/mol
Synonyms	1,3,4-Oxadiazol-2-ylboronic acid pinacol ester; 2-(1,3,4-Oxadiazol-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3,4-oxadiazole; Oxadiazole-2-boronic acid pinacol ester; 2-(Oxadiazolyl)pinacolborane; 2-(1,3,4-Oxadiazol-2-yl)pinacolborane; 2-Pinacolatoboryl-1,3,4-oxadiazole
EINECS	Contact for details

Quality Control

Our 2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1,3,4-Oxadiazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep the container sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.