Description

2-(4-Methoxybenzyloxy)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, multi-functional boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials development. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries who require reliable, high-purity intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used to construct novel heterocyclic compounds with potential herbicidal, fungicidal, or insecticidal activity.
• Material Science: Building block for creating organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) for electronic and photonic applications.
• Chemical Biology & Diagnostics: Employed in the development of molecular probes, sensors, and bioconjugates due to its reactive boronate functionality.
• Academic & Contract Research: Vital reagent for methodological development in organic synthesis and catalysis research within R&D laboratories.
• Scale-up Process Development: Serves as a validated intermediate for pilot plant and commercial-scale manufacturing processes requiring robust coupling partners.

Basic Information

Product Name	2-(4-Methoxybenzyloxy)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1346708-08-4
Molecular Formula	C20H26BNO4
Molecular Weight	355.24 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-[(4-methoxyphenyl)methoxy]pyridine; 2-((4-Methoxybenzyl)oxy)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-Pinacolatoboryl-2-(4-methoxybenzyloxy)pyridine; 2-(PMB-oxy)-4-Bpin-pyridine; 1346708-08-4; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-[(4-methoxybenzyl)oxy]pyridine
EINECS	Contact for details

Quality Control

Our 2-(4-Methoxybenzyloxy)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.