Description

2-(Cyclohexyloxy)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is a high-value, organoboron building block essential for modern synthetic chemistry, particularly in cross-coupling reactions. Its core value lies in enabling the precise and efficient construction of complex molecular architectures, which is critical for developing new active compounds. This advanced intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries, as well as by fine chemical manufacturers specializing in custom synthesis and process development.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and this boronic ester pinacol ester, enabling the synthesis of complex biaryl and heterobiaryl structures.
• Pharmaceutical Intermediate: Serves as a critical building block in the research and development of novel active pharmaceutical ingredients (APIs), especially those containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents and herbicides where specific heterocyclic systems are required for biological activity.
• Material Science Research: Employed in the development of organic electronic materials, such as ligands for OLEDs or conductive polymers, due to its functionalized pyridine-boronate structure.
• Chemical Biology & Probe Development: Useful for synthesizing molecular probes and labeled compounds for biochemical assays and diagnostic research.
• Custom & Contract Synthesis: A valuable starting material for fine chemical companies offering bespoke synthesis services to clients in various high-tech industries.

Basic Information

Product Name	2-(Cyclohexyloxy)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
CAS No.	1346707-98-9
Molecular Formula	C₁₇H₂₆BNO₃
Molecular Weight	303.21 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(cyclohexyloxy)pyridine; 2-Cyclohexyloxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-(Cyclohexyloxy)pyridine-4-boronic acid pinacol ester; 4-Borono-2-(cyclohexyloxy)pyridine pinacol ester; Pyridine, 2-(cyclohexyloxy)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 1346707-98-9
EINECS	Contact for details

Quality Control

Our 2-(Cyclohexyloxy)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR (¹H and ¹³C), and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters. We support our clients' regulatory needs and can supply material suitable for research and development under cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C (refrigerated). Allow the sealed container to equilibrate to room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.