Description

2-Propoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, functionalized pyridine boronic ester derivative. This compound is a critical advanced pharmaceutical intermediate and versatile Suzuki-Miyaura cross-coupling building block, enabling the synthesis of complex molecules. It is essential for R&D and production in the pharmaceutical, agrochemical, and material science industries, where precise molecular construction is required.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other small-molecule drug discovery programs.
• Suzuki-Miyaura Cross-Coupling Reactions: Enables the formation of carbon-carbon bonds between the pyridine ring and aryl/heteroaryl halides, a cornerstone of modern medicinal chemistry.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with enhanced properties.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those used in OLEDs and conductive polymers.
• Chemical Biology Probes: Useful for creating tagged molecules to study biological pathways and protein interactions.

Basic Information

Product Name	2-Propoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1346707-85-4
Molecular Formula	C14H22BNO3
Molecular Weight	263.14 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-propoxy-pyridine; 2-Propoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-(2-Propoxy)-pyridineboronic acid pinacol ester; 2-Propoxy-4-pyridineboronic acid pinacol ester; 4-(Pinacolboryl)-2-propoxypyridine; 2-Propoxy-4-(pinacolboron)pyridine; CAS 1346707-85-4
EINECS	Contact for details

Quality Control

Every batch of our 2-Propoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is produced and tested under strict quality management systems. We guarantee high purity and batch-to-batch consistency to meet the rigorous demands of pharmaceutical and advanced synthetic applications. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.