Description

5,6-Dihydro-4H-Pyrrolo[1,2-B]Pyrazol-3-Ylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and advanced intermediates. Its specific fused heterocyclic structure makes it particularly valuable for creating complex molecular architectures with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Serves as a precursor for organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and protein functions.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries via parallel and combinatorial chemistry approaches.
• Catalyst and Ligand Development: Acts as a starting material for synthesizing novel catalysts and ligands used in asymmetric synthesis.

Basic Information

Item	Details
Product Name	5,6-Dihydro-4H-Pyrrolo[1,2-B]Pyrazol-3-Ylboronic Acid
CAS No.	1346526-58-6
Molecular Formula	C7H9BN2O2
Molecular Weight	163.97 g/mol
Synonyms	5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole-3-boronic acid; (5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)boronic acid; 4H-Pyrrolo[1,2-b]pyrazole-3-boronic acid, 5,6-dihydro-; 3-Borono-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole; 1346526-58-6; Boronic acid, B-(5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-
EINECS	Contact for details

Quality Control

Our 5,6-Dihydro-4H-Pyrrolo[1,2-B]Pyrazol-3-Ylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Standard quality parameters include assay (HPLC), identity confirmation (NMR, IR), and control of residual solvents and moisture. A comprehensive Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C (refrigerated). Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥95.0% (Area %)
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.