Description

5-(2-Hydroxy-2-Propyl)-2-Methylphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in medicinal chemistry programs targeting complex biaryl structures.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the boronic ester functionality allows for precise carbon-carbon bond formation.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for creating advanced organic electronic materials and emissive layers due to its ability to form conjugated systems.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Facilitates the creation of specialty polymers with tailored properties through controlled polymerization techniques.
• Chemical Biology & Proteomics: Used in the development of molecular probes and activity-based protein profiling (ABPP) agents.

Basic Information

Product Name	5-(2-Hydroxy-2-Propyl)-2-Methylphenylboronic Acid Pinacol Ester
CAS No.	1345961-02-5
Molecular Formula	C₁₇H₂₇BO₃
Molecular Weight	290.21 g/mol
Synonyms	2-Methyl-5-(2-hydroxypropan-2-yl)phenylboronic acid pinacol ester; 5-(2-Hydroxy-2-propyl)-2-methylbenzeneboronic acid pinacol ester; (5-(2-Hydroxypropan-2-yl)-2-methylphenyl)boronic acid pinacol ester; 2-Methyl-5-(2-hydroxy-2-propyl)phenylboronic acid pinacol ester; Boronic acid, B-[5-(1-hydroxy-1-methylethyl)-2-methylphenyl]-, 1,1-dimethylethyl ester; Pinacol [5-(2-hydroxy-2-propyl)-2-methylphenyl]boronate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and manufacturing. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and GC to verify identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) are available upon request, providing full transparency on batch-specific specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.