Description

Chloro{(S)-(-)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]-1,1'-Binaphthyl}(p-Cymene)Ruthenium(Ii)Chloride CAS NO 1345887-44-6 is a high-value, chiral ruthenium complex designed for advanced asymmetric catalysis. This compound matters because it serves as a highly efficient and selective catalyst, enabling the synthesis of complex chiral molecules with high enantiomeric purity. It is primarily needed by research institutions and pharmaceutical companies for the development of active pharmaceutical ingredients (APIs), fine chemicals, and other high-value specialty products.

Application

• Asymmetric Hydrogenation: A premier catalyst for the enantioselective reduction of prochiral olefins, ketones, and imines, a critical step in pharmaceutical synthesis.
• Pharmaceutical Intermediate Synthesis: Enables the production of chiral building blocks and active pharmaceutical ingredients (APIs) with high optical purity.
• Fine Chemical Manufacturing: Used in the synthesis of specialty chemicals, agrochemicals, and flavors & fragrances requiring precise stereochemical control.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis research.
• Process Chemistry Optimization: Employed for scaling up asymmetric transformations from laboratory to pilot plant and production scale.

Basic Information

Item	Details
Product Name	Chloro{(S)-(-)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]-1,1'-Binaphthyl}(p-Cymene)Ruthenium(Ii)Chloride
CAS No.	1345887-44-6
Molecular Formula	C72H68Cl2P2Ru
Molecular Weight	1157.10 g/mol
Synonyms	(S)-Ru(cymene)Cl[(3,5-Me2C6H3)2P]2Binaphthyl; (S)-Ru(cymene)Cl[P(3,5-xylyl)2]2Binaphthyl; (S)-DTBM-SEGPHOS Ru(cymene) chloride; (S)-(-)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]-1,1'-Binaphthyl (p-Cymene)Ruthenium(II) Chloride; (S)-DTBM-SEGPHOS Ru(cymene)Cl; Ruthenium, chloro[(1,2,3,4,5,6-η)-1-methyl-4-(1-methylethyl)benzene][(11bS)-2,2',6,6'-tetrakis(3,5-dimethylphenyl)[1,1'-binaphthalene]-2,2'-diyl]bis[di(3,5-dimethylphenyl)phosphine]-, (OC-6-33)-, chloride
EINECS	Contact for details

Quality Control

Our Chloro{(S)-(-)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]-1,1'-Binaphthyl}(p-Cymene)Ruthenium(Ii)Chloride is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot is characterized by advanced analytical techniques, including NMR and HPLC, to confirm identity, chiral purity, and chemical purity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., argon or nitrogen) at 2-8°C to maintain stability and prevent decomposition. This material is easily oxidized and light-sensitive. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Orange to red-brown solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Chiral Purity (HPLC)	≥ 99% ee
Solubility	Soluble in common organic solvents (DCM, THF, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.