Description

3'-Bromo-[1,1'-Biphenyl]-3,5-Dicarbonitrile is a high-purity, functionalized biphenyl derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of pharmaceuticals, agrochemicals, and functional materials, enabling complex molecular architectures. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for scale-up and production.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogen and nitrile functionality.
• Material Science Research: Serves as a monomer or building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for transition metal catalysis and asymmetric synthesis.
• Chemical Biology Probes: Acts as a core structure for developing fluorescent tags or molecular probes for biological imaging and assay development.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the bromine substituent.

Basic Information

Product Name	3'-Bromo-[1,1'-Biphenyl]-3,5-Dicarbonitrile
CAS No.	1345508-87-3
Molecular Formula	C14H7BrN2
Molecular Weight	283.13 g/mol
Synonyms	[1,1'-Biphenyl]-3,5-dicarbonitrile, 3'-bromo-; 3'-Bromo-3,5-dicyanobiphenyl; 3-Bromo-5-cyanophenylbenzonitrile; 3'-Bromobiphenyl-3,5-dicarbonitrile; 3,5-Dicyano-3'-bromobiphenyl; 3'-Bromo-[1,1'-biphenyl]-3,5-dicarbonitrile; 3'-Bromobiphenyl-3,5-dinitrile
EINECS	Contact for details

Quality Control

Our 3'-Bromo-[1,1'-Biphenyl]-3,5-Dicarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.