Description

Ethyl (2E)-3-[2-Bromo-5-(Trifluoromethyl)Phenyl]Prop-2-Enoate is a high-value, multi-functional chemical intermediate characterized by its bromo- and trifluoromethyl-substituted aromatic core. This compound matters for its role as a key building block in the synthesis of complex molecules, offering a versatile handle for further functionalization via cross-coupling reactions and other transformations. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients, as well as by fine chemical manufacturers producing advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors for OLEDs, due to its conjugated system and halogenated structure.
• Custom Synthesis and Contract Manufacturing: A vital component for fine chemical companies offering bespoke synthesis services for clients in life sciences.
• Academic and Industrial R&D: Used in methodological studies and exploration of new chemical spaces in university and corporate research laboratories.

Basic Information

Item	Detail
Product Name	Ethyl (2E)-3-[2-Bromo-5-(Trifluoromethyl)Phenyl]Prop-2-Enoate
CAS No.	1345484-78-7
Molecular Formula	C₁₂H₁₀BrF₃O₂
Molecular Weight	323.11 g/mol
Synonyms	(2E)-3-[2-Bromo-5-(trifluoromethyl)phenyl]-2-propenoic acid ethyl ester; Ethyl (E)-3-(2-Bromo-5-(trifluoromethyl)phenyl)acrylate; 2-Bromo-5-(trifluoromethyl)cinnamic acid ethyl ester; (E)-Ethyl 3-(2-bromo-5-(trifluoromethyl)phenyl)acrylate; Ethyl 3-(2-Bromo-alpha,alpha,α-trifluoro-p-tolyl)acrylate; 1345484-78-7; AKOS006361889
EINECS	Contact for details

Quality Control

Every batch of Ethyl (2E)-3-[2-Bromo-5-(Trifluoromethyl)Phenyl]Prop-2-Enoate is produced and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled under an inert atmosphere for prolonged storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.