Description

tert-Butyl 5,6-Dihydro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2-Oxopyridine-1(2H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a valuable boronic ester functional group. This compound is critical for enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are foundational to modern medicinal chemistry. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active compounds and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for small molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds to construct complex, functionalized heterocyclic systems essential for drug discovery.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides requiring specific boronate-containing structures.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of advanced organic electronic materials and polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Process Chemistry & Scale-Up: Supports route scouting and optimization for the efficient, large-scale manufacturing of target molecules.

Basic Information

Product Name	tert-Butyl 5,6-Dihydro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2-Oxopyridine-1(2H)-Carboxylate
CAS No.	1345469-26-2
Molecular Formula	C16H28BNO5
Molecular Weight	325.21 g/mol
Synonyms	1-Boc-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5,6-dihydro-2(1H)-pyridinone; tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-oxo-1,2,5,6-tetrahydropyridine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,5,6-tetrahydropyridin-2-one; 4-Pinacolatoboryl-1-Boc-1,2,5,6-tetrahydropyridin-2-one; 1-Boc-4-(pinacolatoboryl)-5,6-dihydro-2(1H)-pyridinone; 4-BPin-1-Boc-2-piperidone (5,6-dihydro); CAS 1345469-26-2
EINECS	Contact for details

Quality Control

Our tert-Butyl 5,6-Dihydro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2-Oxopyridine-1(2H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided to guarantee compliance with your research and process development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Assay	≥95.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.