Description

1,3,2-Dioxaborolane, 2-(3,5-Dimethoxy-4-Methylphenyl)-4,4,5,5-Tetramethyl- is a highly functionalized pinacol boronic ester derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its value lies in its stability and reactivity, making it a superior alternative to boronic acids for challenging cross-coupling reactions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks for complex molecule synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for Suzuki-Miyaura cross-coupling reactions to form biaryl and heterobiaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aryl-boron motifs.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs and OFETs, where precise molecular architecture is crucial.
• Chemical Biology & Probe Development: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes and tags used in diagnostic and imaging applications.
• Academic & Process R&D: Serves as a reliable reagent for methodology development and scaling up synthetic routes in both academic and industrial laboratory settings.

Basic Information

Item	Details
Product Name	1,3,2-Dioxaborolane, 2-(3,5-Dimethoxy-4-Methylphenyl)-4,4,5,5-Tetramethyl-
CAS No.	1345024-09-0
Molecular Formula	C₁₇H₂₇BO₄
Molecular Weight	306.21 g/mol
Synonyms	2-(3,5-Dimethoxy-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (3,5-Dimethoxy-4-methylphenyl)boronic acid pinacol ester; 4-Methyl-3,5-dimethoxyphenylboronic acid pinacol ester; Pinacol (3,5-dimethoxy-4-methylphenyl)boronate; 3,5-Dimethoxy-4-methylbenzeneboronic acid pinacol ester; Boronic acid, B-(3,5-dimethoxy-4-methylphenyl)-, 1,1-dimethylethyl ester (9CI); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of our 1,3,2-Dioxaborolane derivative is manufactured and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy for comprehensive characterization. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, we recommend storing the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Optimal storage temperature is 2-8°C (refrigerated) for extended shelf life.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥96.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.