Description

1-(4-Bromobutyl)-2-Fluorobenzene is a valuable fluorinated and brominated aromatic building block used in advanced organic synthesis. This compound matters for its dual functionalization, offering versatile reactivity for constructing complex molecular architectures. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic moieties for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can improve biological activity and environmental persistence.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic semiconductors and liquid crystal molecules used in display technologies.
• Cross-Coupling Reactions: The bromobutyl chain acts as a handle for further functionalization via palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi).
• Polymer Modification: Employed to introduce fluorinated phenyl groups into polymer backbones to alter physical properties like solubility, thermal stability, and surface energy.
• Chemical Biology Probes: Useful for synthesizing fluorinated probes and tags for studying biological systems and drug-target interactions.

Basic Information

Product Name	1-(4-Bromobutyl)-2-Fluorobenzene
CAS No.	1343287-81-9
Molecular Formula	C10H12BrF
Molecular Weight	231.11 g/mol
Synonyms	2-Fluoro-1-(4-bromobutyl)benzene; 1-Bromo-4-(2-fluorophenyl)butane; 4-(2-Fluorophenyl)butyl bromide; o-Fluoro-ω-bromobutylbenzene; (2-Fluorophenyl)butyl bromide; 2-Fluorobenzylbutyl bromide (common name variant); 1-(4-Bromobutyl)-2-fluorobenzene; 4-Bromobutyl-2-fluorobenzene
EINECS	Contact for details

Quality Control

Our 1-(4-Bromobutyl)-2-Fluorobenzene is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.