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2,4-Diphenyl-6-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Pyrimidine CAS NO 1342892-16-3


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CAS No.:1342892-16-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,4-Diphenyl-6-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Pyrimidine is a high-value, synthetically versatile boronic ester pinacol ester derivative, serving as a critical building block in modern organic synthesis. Its core value lies in enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise, scalable intermediates for developing active ingredients and functional organic compounds.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for targeted therapies and kinase inhibitors.
  • Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
  • Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport materials and host materials in display and lighting technologies.
  • Material Science Research: Employed in the development of organic semiconductors, conductive polymers, and metal-organic frameworks (MOFs).
  • Cross-Coupling Reactions: A reliable boron reagent for Suzuki-Miyaura coupling to form biaryl and heterobiaryl structures central to many functional molecules.
  • Chemical Biology & Diagnostics: Utilized in probe and sensor development for bioimaging and diagnostic assays.

Basic Information

Product Name 2,4-Diphenyl-6-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Pyrimidine
CAS No. 1342892-16-3
Molecular Formula C28H27BN2O2
Molecular Weight 434.34 g/mol
Synonyms 6-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-2,4-diphenylpyrimidine; 2,4-Diphenyl-6-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyrimidine; 2,4-Diphenyl-6-(3-(pinacolboryl)phenyl)pyrimidine; 3-(2,4-Diphenylpyrimidin-6-yl)phenylboronic acid pinacol ester; Boronic acid, B-[3-(2,4-diphenyl-6-pyrimidinyl)phenyl]-, 1,1-dimethylethyl ester
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Quality Control

Every batch of 2,4-Diphenyl-6-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Pyrimidine is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity, meeting the stringent requirements for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when dispensing to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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