Description

1-(3-Chloro-2-Fluorophenyl)-2-Methylpropan-1-One CAS NO 1341641-88-0 is a high-purity fluorinated aromatic ketone building block of significant importance in advanced organic synthesis. Its core value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists working on novel active ingredients, where its specific halogen substitution pattern enables precise structural modifications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Serves as a critical building block for developing new-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and halogenated structure.
• Chemical Biology & Proteomics: Employed as a reactive handle or linker in the design of molecular probes, enzyme inhibitors, and bioconjugation reagents.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	1-(3-Chloro-2-Fluorophenyl)-2-Methylpropan-1-One
CAS No.	1341641-88-0
Molecular Formula	C10H10ClFO
Molecular Weight	200.64 g/mol
Synonyms	3'-Chloro-2'-fluoro-2-methylpropiophenone; 2-Methyl-1-(3-chloro-2-fluorophenyl)propan-1-one; 1-Propanone, 1-(3-chloro-2-fluorophenyl)-2-methyl-; α,α-Dimethyl-3-chloro-2-fluorobenzeneacetyl; (3-Chloro-2-fluorophenyl) isobutyryl ketone
EINECS	Contact for details

Quality Control

Our production of 1-(3-Chloro-2-Fluorophenyl)-2-Methylpropan-1-One adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical synthesis. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development under quality management systems suitable for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.