Description

3-Hydroxy-4-Nitrophenylboronic Acid, Pinacol Ester is a protected boronic acid derivative, a crucial intermediate in modern synthetic organic chemistry and pharmaceutical research. Its value lies in the stability provided by the pinacol ester group, which protects the reactive boronic acid functionality during synthetic sequences, making it a versatile building block. This compound is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for applications such as Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those requiring biaryl linkages via cross-coupling chemistry.
• Agrochemical Synthesis: Used in the research and development of novel active ingredients for crop protection products.
• Material Science Research: Serves as a monomer or precursor in the development of advanced organic electronic materials and polymers.
• Suzuki-Miyaura Cross-Coupling Reactions: The protected boronic ester is a stable and convenient reagent for forming carbon-carbon bonds with aryl halides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes.
• Ligand and Catalyst Development: Acts as a precursor for creating novel ligands and organometallic catalysts.

Basic Information

Product Name	3-Hydroxy-4-Nitrophenylboronic Acid, Pinacol Ester
CAS No.	1339927-68-2
Molecular Formula	C12H16BNO5
Molecular Weight	265.07 g/mol
Synonyms	4-Nitro-3-hydroxyphenylboronic acid pinacol ester; 2-(4-Nitro-3-hydroxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane; 3-Hydroxy-4-nitrophenylboronic acid pinacol cyclic ester; Pinacol (3-Hydroxy-4-nitrophenyl)boronate; (3-Hydroxy-4-nitrophenyl)boronic acid pinacol ester; Boronic acid, B-(3-hydroxy-4-nitrophenyl)-, 1,1-dimethylethyl ester (9CI)
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-4-Nitrophenylboronic Acid, Pinacol Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all specifications are available upon request, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.