Description

1-(3-Oxetanyl)-1H-Pyrazole-4-Boronic Acid Pinacol Ester is a high-value, organoboron building block designed for advanced synthetic chemistry. This compound matters as a critical reagent in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. Pharmaceutical researchers and agrochemical developers need it for creating novel active ingredients, particularly in medicinal chemistry for drug discovery programs.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds to construct complex biaryl and heteroaryl structures in medicinal chemistry.
• Pharmaceutical Intermediate: Serves as a versatile building block in the synthesis of potential drug candidates, especially those containing pyrazole and oxetane pharmacophores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its conjugated system.
• Chemical Biology Probes: Facilitates the synthesis of labeled compounds and molecular probes for studying biological pathways and target engagement.
• Library Synthesis for High-Throughput Screening: Enables the rapid generation of diverse compound libraries to identify new bioactive molecules.

Basic Information

Item	Details
Product Name	1-(3-Oxetanyl)-1H-Pyrazole-4-Boronic Acid Pinacol Ester
CAS No.	1339890-99-1
Molecular Formula	C12H19BN2O3
Molecular Weight	250.11 g/mol
Synonyms	1-(Oxetan-3-yl)-1H-pyrazole-4-boronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(oxetan-3-yl)-1H-pyrazole; 1-(Oxetan-3-yl)-1H-pyrazole-4-boronic acid, pinacol ester; 1-(3-Oxetanyl)-1H-pyrazole-4-boronic acid neopentyl glycol ester (common alternative); 1-Oxetan-3-yl-1H-pyrazole-4-boronic acid pinacol ester; 3-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)oxetane
EINECS	Contact for details

Quality Control

Our 1-(3-Oxetanyl)-1H-Pyrazole-4-Boronic Acid Pinacol Ester is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container for use to prevent degradation. For long-term storage, consider storing under an inert gas blanket.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.