Description

4,4,5,5-Tetramethyl-2-[3-(2-Methylpropoxy)Phenyl]-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester building block essential for modern synthetic chemistry. This compound is a critical intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and organic electronic materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common structural motif in pharmaceuticals and agrochemicals.
• Pharmaceutical Intermediate: Used in the research and development of new drug candidates, particularly for creating complex, functionalized aromatic systems.
• Agrochemical Synthesis: Serves as a building block for novel herbicides, fungicides, and insecticides requiring specific aryl-boronate functionality.
• Material Science Research: Employed in the synthesis of organic semiconductors, ligands for catalysts, and other advanced functional materials.
• Chemical Biology & Proteomics: Can be used to develop molecular probes and affinity tags due to its selective reactivity.
• Scale-up Process Chemistry: Suitable for transitioning from laboratory-scale discovery to pilot and commercial-scale manufacturing of fine chemicals.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-[3-(2-Methylpropoxy)Phenyl]-1,3,2-Dioxaborolane
CAS No.	1338916-31-6
Molecular Formula	C16H25BO3
Molecular Weight	276.18 g/mol
Synonyms	3-(Isobutoxy)phenylboronic acid pinacol ester; 3-(2-Methylpropoxy)benzeneboronic acid pinacol ester; [3-(Isobutoxy)phenyl]boronic acid pinacol ester; 3-Isobutoxyphenylboronic acid pinacol ester; 1,3,2-Dioxaborolane, 2-[3-(2-methylpropoxy)phenyl]-4,4,5,5-tetramethyl-; PINACOL 3-ISOBUTOXYPHENYLBORONATE
EINECS	Contact for details

Quality Control

Every batch of our 4,4,5,5-Tetramethyl-2-[3-(2-Methylpropoxy)Phenyl]-1,3,2-Dioxaborolane is manufactured and tested under strict quality management systems. We ensure high purity and lot-to-lot consistency through advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged manipulations to prevent hydrolysis and maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.