Description

2-(5-Butylthiophen-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. This compound is essential for enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex organic molecules.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing biaryl and heterobiaryl motifs prevalent in active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and insecticides that require specific thiophene-based architectures.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for synthesizing electron-transport or emissive layer materials in display and lighting technologies.
• Polymer and Material Science: Employed to create functionalized monomers for conductive polymers, organic semiconductors, and specialty coatings.
• Academic and Industrial R&D: A versatile tool for methodology development and exploring new chemical spaces in medicinal and synthetic chemistry laboratories.

Basic Information

Product Name	2-(5-Butylthiophen-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1338083-26-3
Molecular Formula	C₁₄H₂₃BO₂S
Molecular Weight	266.21 g/mol
Synonyms	5-Butyl-2-thiopheneboronic acid pinacol ester; 2-(5-Butylthiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Butylthiophene-2-boronic acid pinacol ester; (5-Butylthiophen-2-yl)boronic acid pinacol ester; 2-(5-n-Butylthiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (5-butylthiophen-2-yl)boronate; 5-Butyl-2-thienylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 2-(5-Butylthiophen-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured and tested under strict quality management systems to ensure consistency and reliability for sensitive coupling reactions. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and other relevant analytical methods are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.