Description

1-Chloroisoquinoline-8-Carbaldehyde is a high-purity, versatile heterocyclic building block and key synthetic intermediate. This compound is valued for its reactive aldehyde and halogenated quinoline functionalities, enabling precise molecular construction in advanced chemical synthesis. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug candidates, particularly those targeting neurological disorders and oncology.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides due to its bioactive quinoline core.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and production of organic electronic materials, such as OLEDs and sensors.
• Chemical Biology: Utilized as a probe or labeling agent in biochemical research and diagnostic assay development.
• Custom Synthesis: A key building block for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	1-Chloroisoquinoline-8-Carbaldehyde
CAS No.	1337879-86-3
Molecular Formula	C10H6ClNO
Molecular Weight	191.61 g/mol
Synonyms	8-Isoquinolinecarboxaldehyde, 1-chloro-; 1-Chloro-8-isoquinolinecarboxaldehyde; 1-Chloro-8-formylisoquinoline; 1-Chloroisoquinoline-8-carboxaldehyde; 1337879-86-3; 8-Formyl-1-chloroisoquinoline; 1-Chloro-8-ald-isoquinoline
EINECS	Contact for details

Quality Control

Our 1-Chloroisoquinoline-8-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in GMP-related synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere for prolonged procedures to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.