Description

(2,4,5-Trimethylphenyl)Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex organic molecules. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of new active ingredients and functional compounds.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl structures, a common motif in pharmaceuticals and organic electronics.
• Pharmaceutical Intermediate: Used in the research and development of novel active pharmaceutical ingredients (APIs), particularly for creating sterically hindered aryl systems.
• Agrochemical Synthesis: Employed in the production of advanced herbicides, fungicides, and insecticides that require specific, multi-substituted aromatic frameworks.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Applied in the synthesis of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) due to its defined molecular geometry.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological processes and protein interactions.

Basic Information

Product Name	(2,4,5-Trimethylphenyl)Boronic Acid Pinacol Ester
CAS No.	1337505-78-8
Molecular Formula	C15H23BO2
Molecular Weight	246.15 g/mol
Synonyms	2,4,5-Trimethylbenzeneboronic Acid Pinacol Ester; (2,4,5-Trimethylphenyl)boronic Acid Pinacol Ester; Pinacol (2,4,5-Trimethylphenyl)boronate; B-(2,4,5-Trimethylphenyl)boronic Acid Pinacol Ester; 4,4,5,5-Tetramethyl-2-(2,4,5-trimethylphenyl)-1,3,2-dioxaborolane; 2,4,5-Trimethylphenylboronic Acid Pinacol Ester; (2,4,5-Trimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our (2,4,5-Trimethylphenyl)Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is analyzed using advanced techniques including NMR, HPLC, and GC to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.