Description

3-(2-Fluorophenyl)Azetidin-3-Ol is a high-purity, synthetically valuable azetidine derivative. This compound serves as a critical chiral building block and intermediate in modern pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of new drug candidates targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its constrained azetidine ring and fluorine substitution.
• Process Chemistry & Scale-up: Serves as a starting material or advanced intermediate in the development of scalable, cost-effective synthetic routes for active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Potential building block for creating novel herbicides, fungicides, or insecticides with improved efficacy and environmental profiles.
• Chemical Biology Probes: Useful for the synthesis of molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring high-purity, complex heterocyclic intermediates.

Basic Information

Item	Details
Product Name	3-(2-Fluorophenyl)Azetidin-3-Ol
CAS No.	1335048-77-5
Molecular Formula	C9H10FNO
Molecular Weight	167.18 g/mol
Synonyms	3-(2-Fluorophenyl)-3-hydroxyazetidine; 3-Hydroxy-3-(2-fluorophenyl)azetidine; 3-(2-Fluorophenyl)azetidin-3-ol; 2-Fluoro-β-(3-hydroxyazetidin-3-yl)benzene; Azetidin-3-ol, 3-(2-fluorophenyl)-; 1335048-77-5; 3-(2-Fluorophenyl)-3-azetidinol
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Fluorophenyl)Azetidin-3-Ol is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.