Description

4-Fluoropiperidin-3-Ol Hydrochloride CAS NO 1334416-55-5 is a high-purity fluorinated piperidine derivative, a crucial building block in modern pharmaceutical and agrochemical research. This compound is valued for its role as a versatile synthetic intermediate, enabling the introduction of both fluorine and hydroxyl functional groups into complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical industry for the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study enzyme function and biological pathways.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organocatalysts for asymmetric synthesis.
• Material Science Precursor: Potential use in the synthesis of advanced polymers and functional materials with specific fluorinated properties.

Basic Information

Product Name	4-Fluoropiperidin-3-Ol Hydrochloride
CAS No.	1334416-55-5
Molecular Formula	C5H11ClFNO
Molecular Weight	155.60 g/mol
Synonyms	3-Hydroxy-4-fluoropiperidine hydrochloride; 4-Fluoro-3-hydroxypiperidine hydrochloride; 4-Fluoro-3-piperidinol hydrochloride; 4-Fluoropiperidin-3-ol HCl; 3-Piperidinol, 4-fluoro-, hydrochloride (1:1); 4-Fluoro-3-hydroxy-piperidine HCl salt
EINECS	Contact for details

Quality Control

Our 4-Fluoropiperidin-3-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.