Description

2-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-1H-Indole is a high-value, advanced pharmaceutical intermediate featuring a unique indole core linked to a pinacol boronate ester. This compound is critical for enabling efficient cross-coupling reactions, particularly in the synthesis of complex molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reagent: A key building block for forming carbon-carbon bonds in the synthesis of complex organic molecules and heterocycles.
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, especially those containing indole or biaryl motifs.
• Agrochemical Synthesis: Serves as a precursor in the creation of new herbicides, fungicides, and insecticides with enhanced properties.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology Probes: Useful for creating tagged molecules to study biological processes and protein interactions.
• Catalyst and Ligand Development: Acts as a starting material for synthesizing novel catalysts and ligands used in asymmetric synthesis.

Basic Information

Product Name	2-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-1H-Indole
CAS No.	1333340-59-2
Molecular Formula	C20H22BNO2
Molecular Weight	319.21 g/mol
Synonyms	3-(1H-Indol-2-yl)phenylboronic acid pinacol ester; 2-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1H-indole; [3-(1H-Indol-2-yl)phenyl]boronic acid pinacol ester; 2-(3-Boronophenyl)-1H-indole pinacol ester; 3-(1H-Indol-2-yl)benzeneboronic acid pinacol ester; Pinacol [3-(1H-indol-2-yl)phenyl]boronate; CAS 1333340-59-2
EINECS	Contact for details

Quality Control

Every batch of 2-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-1H-Indole undergoes rigorous analytical testing to ensure high purity and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and cGMP manufacturing environments. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.