Description

4-[3-(4,4,5,5-Tetramethyl- {1,3,2}Dioxaborolan-2-Yl)-Phenyl]-Thiomorpholine 1,1-Dioxide is a high-value, advanced pharmaceutical intermediate and building block featuring a protected boronic ester functional group. This compound is critical for enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for forming carbon-carbon bonds. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Serves as a monomer or precursor in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Synthesis: Enables efficient Suzuki-Miyaura cross-coupling to introduce the thiomorpholine dioxide moiety into complex molecular architectures.
• Ligand & Catalyst Development: Utilized in the design of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Life Science Research: Acts as a crucial probe or tool compound in biochemical and pharmacological studies.

Basic Information

Product Name	4-[3-(4,4,5,5-Tetramethyl- {1,3,2}Dioxaborolan-2-Yl)-Phenyl]-Thiomorpholine 1,1-Dioxide
CAS No.	1333263-95-8
Molecular Formula	C16H24BNO4S
Molecular Weight	337.24 g/mol
Synonyms	3-(1,1-Dioxidothiomorpholin-4-yl)phenylboronic acid pinacol ester; 4-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]thiomorpholine 1,1-dioxide; 3-(Thiomorpholine-1,1-dioxide-4-yl)phenylboronic acid pinacol ester; (3-(1,1-Dioxidothiomorpholino)phenyl)boronic acid pinacol ester; 4-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)thiomorpholine 1,1-dioxide; Boronic acid, B-[3-(1,1-dioxide-4-thiomorpholinyl)phenyl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our 4-[3-(4,4,5,5-Tetramethyl- {1,3,2}Dioxaborolan-2-Yl)-Phenyl]-Thiomorpholine 1,1-Dioxide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.