Description

(3-((4-Methylpiperidin-1-Yl)Methyl)Phenyl)Boronic Acid is a sophisticated boronic acid derivative featuring a 4-methylpiperidine moiety, making it a valuable building block in modern synthetic chemistry. Its primary value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, leveraging the piperidine scaffold.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products through palladium-catalyzed cross-coupling reactions.
• Material Science Research: Serves as a monomer or building block for constructing organic electronic materials, such as those used in OLEDs or sensors.
• Ligand and Catalyst Development: The boronic acid group and nitrogen-containing heterocycle make it useful for developing novel ligands for catalysis.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological processes and protein interactions.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries via high-throughput parallel synthesis techniques.

Basic Information

Product Name	(3-((4-Methylpiperidin-1-Yl)Methyl)Phenyl)Boronic Acid
CAS No.	1332746-94-7
Molecular Formula	C13H20BNO2
Molecular Weight	233.12 g/mol
Synonyms	[3-[(4-Methyl-1-piperidinyl)methyl]phenyl]boronic acid; (3-((4-Methylpiperidin-1-yl)methyl)phenyl)boronic acid; Boronic acid, B-[3-[(4-methyl-1-piperidinyl)methyl]phenyl]-; 3-((4-Methylpiperidin-1-yl)methyl)benzeneboronic acid; (3-((4-Methyl-1-piperidinyl)methyl)phenyl)boronic acid; 1-Piperidinecarboxylic acid, 4-methyl-, 3-boronobenzyl ester (tautomeric form)
EINECS	Contact for details

Quality Control

Our (3-((4-Methylpiperidin-1-Yl)Methyl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.