Description

(3E)-4-(3-Bromo-4-Methoxyphenyl)But-3-En-2-One is a high-purity, synthetically valuable organic intermediate characterized by its α,β-unsaturated ketone (enone) structure substituted with bromo and methoxy aromatic groups. This compound is essential for advanced pharmaceutical research and fine chemical synthesis, serving as a versatile building block for constructing complex molecular architectures. It is primarily needed by pharmaceutical R&D laboratories, agrochemical manufacturers, and specialty chemical producers engaged in developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators, leveraging its halogenated aromatic moiety.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the creation of molecular probes and tags for studying enzyme activity and protein interactions due to its reactive enone functionality.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing novel chiral ligands and organocatalysts for asymmetric synthesis.
• Academic & Industrial R&D: A fundamental building block in organic chemistry research for methodology development and complex natural product synthesis.

Basic Information

Product Name	(3E)-4-(3-Bromo-4-Methoxyphenyl)But-3-En-2-One
CAS No.	1331560-65-6
Molecular Formula	C11H11BrO2
Molecular Weight	255.11 g/mol
Synonyms	(E)-4-(3-Bromo-4-methoxyphenyl)but-3-en-2-one; 3-Bromo-4-methoxybenzalacetone; 1-(3-Bromo-4-methoxyphenyl)-3-buten-2-one (E)-; 4-(3-Bromo-4-methoxyphenyl)-3-buten-2-one; (E)-4-(3-Bromo-4-methoxyphenyl)-3-buten-2-one; (3E)-4-(3-Bromo-4-methoxyphenyl)-3-buten-2-one; 3'-Bromo-4'-methoxychalcone (unsaturated ketone derivative); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our (3E)-4-(3-Bromo-4-Methoxyphenyl)But-3-En-2-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP and ISO 9001 standards to meet the stringent requirements of global pharmaceutical and fine chemical supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0% (Area Percent)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.