Description

O,o-Diethyl Thiophosphate-13C4 Ammonium Salt is a stable ammonium salt form of a carbon-13 labeled organophosphorus compound. This isotopically labeled material is essential for advanced analytical research, providing a critical internal standard for precise quantification and metabolic pathway tracing. It is primarily required by analytical laboratories, agrochemical research facilities, and pharmaceutical development teams engaged in sophisticated mass spectrometry (MS) and nuclear magnetic resonance (NMR) studies.

Application

• Internal Standard for Mass Spectrometry (MS): Used for the accurate quantification of organophosphate pesticides, their metabolites, or related compounds in environmental, food safety, and biological samples.
• Metabolic Pathway Tracing: Serves as a labeled precursor or tracer in studies investigating the environmental fate, biodegradation, or metabolic pathways of thiophosphate esters.
• NMR Spectroscopy Studies: Provides a carbon-13 enriched probe for structural elucidation and dynamic studies of organophosphorus molecules in solution.
• Analytical Method Development & Validation: Critical for developing and validating highly sensitive and specific LC-MS/MS or GC-MS methods in regulatory and research settings.
• Agrochemical Research: Employed in the research and development of new pesticides, specifically in studies related to mode of action, environmental persistence, and residue analysis.
• Pharmaceutical Impurity Profiling: Can be utilized as a reference standard for identifying and quantifying potential genotoxic impurities derived from thiophosphorylating agents in drug substances.

Basic Information

Product Name	O,o-Diethyl Thiophosphate-13C4 Ammonium Salt
CAS No.	1330162-89-4
Molecular Formula	C213C4H16NO3PS
Molecular Weight	~235.19 g/mol (for 13C4 labeled form)
Synonyms	Ammonium O,O-Diethyl Thiophosphate-13C4; Diethyl Thiophosphate-13C4 Ammonium Salt; (13C4)-Diethyl Phosphorothioate Ammonium Salt; DETP-13C4 Ammonium Salt; Ammonium Diethyl (13C4)Phosphorothioate; Phosphorothioic Acid O,O-Diethyl Ester-13C4 Ammonium Salt; AE 13C4 Ammonium Salt
EINECS	Contact for details

Quality Control

Every batch of O,o-Diethyl Thiophosphate-13C4 Ammonium Salt is produced and analyzed under strict quality management protocols. We ensure high chemical purity and isotopic enrichment suitable for sensitive analytical applications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications for isotopic purity (e.g., 13C atom %), chemical purity (by HPLC/NMR), and identity confirmation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Purity (13C atom %)	≥ 99%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.