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3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thieno[2,3-C]Pyridine CAS NO 1326713-87-4


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CAS No.:1326713-87-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thieno[2,3-C]Pyridine is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex pharmaceutical and agrochemical intermediates. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality coupling partners for drug discovery and advanced material synthesis.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing the thienopyridine scaffold.
  • Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling.
  • Material Science Research: Serves as a building block for creating organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
  • Chemical Biology & Medicinal Chemistry: Employed in the construction of molecular probes and libraries for high-throughput screening and structure-activity relationship (SAR) studies.
  • Catalyst & Ligand Development: Acts as a substrate or precursor in the development of new catalytic systems and specialized ligands.
  • Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and complex molecules.

Basic Information

Item Details
Product Name 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thieno[2,3-C]Pyridine
CAS No. 1326713-87-4
Molecular Formula C13H16BNO2S
Molecular Weight 261.15 g/mol
Synonyms Thieno[2,3-c]pyridine-3-boronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thieno[2,3-c]pyridine; 3-(Thieno[2,3-c]pyridin-3-yl)boronic acid pinacol ester; 3-Pinacolatoborylthieno[2,3-c]pyridine; 1326713-87-4; Thieno[2,3-c]pyridin-3-ylboronic acid pinacol ester
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Quality Control

Our 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thieno[2,3-C]Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance in sensitive cross-coupling applications. Certificates of Analysis (COA) with full analytical data are provided for each shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (HPLC) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥97.0%
Water Content (KF) ≤0.5%
Residue on Ignition ≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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