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3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thieno[2,3-C]Pyridine CAS NO 1326713-87-4
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CAS No.:1326713-87-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thieno[2,3-C]Pyridine is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex pharmaceutical and agrochemical intermediates. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality coupling partners for drug discovery and advanced material synthesis.
Application
- Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing the thienopyridine scaffold.
- Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling.
- Material Science Research: Serves as a building block for creating organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
- Chemical Biology & Medicinal Chemistry: Employed in the construction of molecular probes and libraries for high-throughput screening and structure-activity relationship (SAR) studies.
- Catalyst & Ligand Development: Acts as a substrate or precursor in the development of new catalytic systems and specialized ligands.
- Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and complex molecules.
Basic Information
| Item | Details |
|---|---|
| Product Name | 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thieno[2,3-C]Pyridine |
| CAS No. | 1326713-87-4 |
| Molecular Formula | C13H16BNO2S |
| Molecular Weight | 261.15 g/mol |
| Synonyms | Thieno[2,3-c]pyridine-3-boronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thieno[2,3-c]pyridine; 3-(Thieno[2,3-c]pyridin-3-yl)boronic acid pinacol ester; 3-Pinacolatoborylthieno[2,3-c]pyridine; 1326713-87-4; Thieno[2,3-c]pyridin-3-ylboronic acid pinacol ester |
| EINECS | Contact for details |
Quality Control
Our 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thieno[2,3-C]Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance in sensitive cross-coupling applications. Certificates of Analysis (COA) with full analytical data are provided for each shipment to guarantee traceability and compliance with your research or production specifications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity. Keep away from incompatible materials.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (HPLC) | Conforms |
| Identification (NMR) | Conforms |
| Purity (HPLC) | ≥97.0% |
| Water Content (KF) | ≤0.5% |
| Residue on Ignition | ≤0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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