Description

Closantel-13C6 is a stable isotope-labeled analog of the anthelmintic veterinary drug Closantel, specifically labeled with six carbon-13 atoms. This high-purity reference standard is critical for ensuring the accuracy and reliability of quantitative mass spectrometry-based analyses in complex matrices. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, veterinary medicine, and food safety sectors who require definitive methods for drug residue testing, pharmacokinetic studies, and method validation.

Application

• Internal Standard for LC-MS/MS: Primary use as a quantitative internal standard in liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods for the analysis of Closantel.
• Veterinary Drug Residue Testing: Enables precise quantification of Closantel residues in meat, milk, and other animal-derived food products to ensure compliance with maximum residue limits (MRLs).
• Pharmacokinetic and Metabolism Studies: Used in research to track the absorption, distribution, metabolism, and excretion (ADME) of Closantel in animals.
• Method Development and Validation: Serves as a critical component in developing, optimizing, and validating new analytical methods for Closantel detection.
• Quality Control of Pharmaceutical Formulations: Supports assay and impurity profiling of Closantel-containing veterinary pharmaceutical products.
• Forensic and Regulatory Analysis: Provides definitive identification and quantification in regulatory testing and forensic investigations related to veterinary drug use.

Basic Information

Product Name	Closantel-13C6
CAS No.	1325559-20-3
Molecular Formula	C2213C6H14Cl2I2N2O2
Molecular Weight	~677.0 g/mol (exact mass varies with isotopic enrichment)
Synonyms	Closantel (phenyl-13C6); 5-Chloro-N-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-13C6-benzamide; 3',5-Dichloro-2-hydroxy-13C6-benzamide-3,5-diiodo-4'-(4-chlorophenoxy)salicylanilide; [13C6]-Closantel; Closantel-13C6; Isotopically Labeled Closantel; Closantel Internal Standard; Closantel-13C6 Stable Isotope
EINECS	Contact for details

Quality Control

Our Closantel-13C6 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity for critical analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (Atom % 13C), chemical purity by HPLC, and confirmation of structure. We adhere to relevant guidelines for reference standard materials to ensure reliability and traceability in your laboratory.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Enrichment	≥99 atom % 13C (on labeled positions)
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.