Description

4-Chloro-2-Fluoro-3-Methoxyacetophenone, 97% is a high-purity, multi-functional aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring strategically placed chloro, fluoro, and methoxy substituents, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the halogen and methoxy groups contribute to biological activity and metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating specialized aromatic cores in electronic and optoelectronic materials.
• Organic Synthesis & Chemical Research: Employed in academic and industrial laboratories for method development, catalysis studies, and the construction of complex heterocyclic compounds.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing specialized dyes and functional pigments.

Basic Information

Product Name	4-Chloro-2-Fluoro-3-Methoxyacetophenone, 97%
CAS No.	1323966-44-4
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	1-(4-Chloro-2-fluoro-3-methoxyphenyl)ethan-1-one; 4'-Chloro-2'-fluoro-3'-methoxyacetophenone; 2-Fluoro-4-chloro-3-methoxyacetophenone; 3-Methoxy-4-chloro-2-fluoroacetophenone; Acetophenone, 4-chloro-2-fluoro-3-methoxy-; 1323966-44-4; 4-Chloro-2-fluoro-3-methoxyacetophenone
EINECS	Contact for details

Quality Control

Every batch of our 4-Chloro-2-Fluoro-3-Methoxyacetophenone is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive (hygroscopic); ensure containers are sealed tightly after use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.