Description

4-Fluoro-2-(p-Tolylethynyl)Benzaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique alkyne-linked aromatic structure. This compound is critical for the synthesis of complex molecules, offering a versatile aldehyde functional group for further chemical elaboration. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and organic electronic materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly in medicinal chemistry research for new therapeutic agents.
• Organic Synthesis Reagent: Used in cross-coupling reactions, such as Sonogashira couplings, and as a precursor for heterocyclic compounds due to its reactive aldehyde and alkyne groups.
• Material Science Research: Serves as a monomer or precursor in the development of organic semiconductors, liquid crystals, and advanced polymers.
• Agrochemical Development: Employed in the research and synthesis of novel pesticides and herbicides, leveraging its fluorinated aromatic system.
• Chemical Research & Development: Used in academic and industrial R&D labs for methodological studies and exploring new synthetic pathways.

Basic Information

Product Name	4-Fluoro-2-(p-Tolylethynyl)Benzaldehyde
CAS No.	1322091-22-4
Molecular Formula	C₁₆H₁₁FO
Molecular Weight	238.26 g/mol
Synonyms	4-Fluoro-2-[(4-methylphenyl)ethynyl]benzaldehyde; 2-[(4-Methylphenyl)ethynyl]-4-fluorobenzaldehyde; 4-Fluoro-2-(4-methylphenylethynyl)benzaldehyde; p-Tolylethynyl-4-fluoro-2-benzaldehyde; 4-Fluoro-2-(p-tolylethynyl)benzaldehyde; 1322091-22-4; Benzaldehyde, 4-fluoro-2-[(4-methylphenyl)ethynyl]-
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-(p-Tolylethynyl)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.