Description

Methyl 2-Chloro-6-Fluoro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate is a high-value, multi-functional boronic ester derivative that serves as a critical synthetic intermediate. Its core value lies in enabling efficient cross-coupling reactions, specifically Suzuki-Miyaura couplings, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of fluorinated and chlorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific halogenated aromatic structures.
• Material Science Research: Serves as a precursor for creating advanced organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and bioconjugation reagents for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized fine chemicals.
• Academic & R&D Laboratories: Used extensively in medicinal chemistry and synthetic organic chemistry research for method development and library synthesis.

Basic Information

Product Name	Methyl 2-Chloro-6-Fluoro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate
CAS No.	1321613-03-9
Molecular Formula	C14H17BClFO4
Molecular Weight	314.54 g/mol
Synonyms	Methyl 2-Chloro-6-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate; 2-Chloro-6-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid methyl ester; (2-Chloro-6-fluoro-4-(methoxycarbonyl)phenyl)boronic acid pinacol ester; Benzoic acid, 2-chloro-6-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester; Pinacol (2-Chloro-6-fluoro-4-(methoxycarbonyl)phenyl)boronate; CAS 1321613-03-9
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are available upon request. We adhere to strict quality management protocols suitable for R&D and industrial-scale applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.