Description

N,n-Dimethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is a high-value, functionalized pyridine derivative containing a pinacol boronate ester group, making it a crucial building block in modern synthetic chemistry. This compound matters because it serves as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecules for advanced material and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used to construct complex heterocyclic scaffolds found in advanced herbicides, fungicides, and insecticides, contributing to crop protection solutions.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology & Proteomics: Employed as a bioconjugation reagent or a handle for introducing boron-based functionalities into biomolecules for labeling and study.
• Catalyst Ligand Development: The dimethylamino pyridine structure can be utilized to develop novel ligands for transition metal catalysis.
• Academic & Contract Research: Essential for methodology development and synthetic route exploration in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	N,n-Dimethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine
CAS No.	1321518-05-1
Molecular Formula	C13H21BN2O2
Molecular Weight	248.13 g/mol
Synonyms	2-(Dimethylamino)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-dimethylpyridin-2-amine; N,N-Dimethyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine; 2-Amino-N,N-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-Pinacolatoboryl-N,N-dimethyl-2-aminopyridine; 4-BPin-2-(N,N-dimethylamino)pyridine; 2-(N,N-Dimethylamino)-4-(BPin)pyridine; 1321518-05-1
EINECS	Contact for details

Quality Control

Our N,n-Dimethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C (refrigerated) for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.