Description

2-Chloro-6-Methylpyridine-4-Boronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. This compound matters for its crucial role as a key intermediate in the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex biaryl structures. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing new active ingredients and functional molecules. Its specific substitution pattern offers precise control over molecular architecture in target synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Serves as a building block for constructing organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and asymmetric synthesis.
• Chemical Biology Probes: Utilized for labeling and modifying biomolecules to study biological pathways and protein functions.
• Custom Synthesis and Contract Manufacturing: A key reagent for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	2-Chloro-6-Methylpyridine-4-Boronic Acid
CAS No.	1320397-15-6
Molecular Formula	C6H7BClNO2
Molecular Weight	171.39 g/mol
Synonyms	(2-Chloro-6-methylpyridin-4-yl)boronic acid; 2-Chloro-6-methyl-4-pyridineboronic acid; 4-Borono-2-chloro-6-methylpyridine; 2-Chloro-6-picoline-4-boronic acid; 1320397-15-6; 2-Chloro-6-methylpyridine-4-boroninc acid; 2-Chloro-6-methyl-4-pyridinylboronic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Methylpyridine-4-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ICH Q7, and REACH regulations for our global customer base.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.