Description

3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1-Trityl-1H-Pyrazolo[3,4-B]Pyridine is a sophisticated, high-value boronic ester derivative designed for advanced synthetic chemistry. This compound serves as a critical key building block in the synthesis of complex heterocyclic molecules, enabling precise molecular construction. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing drug candidates, particularly those containing the pyrazolopyridine scaffold.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its boronate functionality for selective bond formation.
• Material Science Research: Serves as a monomer or functional unit in the synthesis of organic electronic materials, such as OLEDs or conductive polymers.
• Chemical Biology Probes: Employed in the creation of tagged molecules or inhibitors for studying biological pathways and target engagement.
• Process Chemistry & Scale-up: Provides a protected and stable boronate source for efficient, large-scale synthesis under process conditions.
• Academic & Contract Research: Essential for methodological development and exploring new chemical spaces in university and CRO laboratories.

Basic Information

Item	Details
Product Name	3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1-Trityl-1H-Pyrazolo[3,4-B]Pyridine
CAS No.	1319591-26-8
Molecular Formula	C33H32BN3O2
Molecular Weight	513.44 g/mol
Synonyms	1-Trityl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazolo[3,4-b]pyridine; 1-Trityl-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazolo[3,4-b]pyridine; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-trityl-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(triphenylmethyl)-; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(triphenylmethyl)-1H-pyrazolo[3,4-b]pyridine; 1-Trityl-3-(pinacolboryl)-1H-pyrazolopyridine; 3-Pinacolatoboryl-1-tritylpyrazolo[3,4-b]pyridine
EINECS	Contact for details

Quality Control

Our 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1-Trityl-1H-Pyrazolo[3,4-B]Pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive coupling reactions. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere when appropriate to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.