Description

2-(1-Methyl-1H-Pyrazol-3-Yl)-Pyridine-5-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. This compound is critically important for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern medicinal chemistry and materials science. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors to construct complex heterocyclic architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing pyridine and pyrazole motifs.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds between aromatic and heteroaromatic systems under mild conditions, essential for constructing complex molecules.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require specific heterocyclic frameworks.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for OLEDs and other functional polymers.
• Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): A valuable linker component in the design of bifunctional molecules for targeted protein degradation.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and the exploration of new chemical space.

Basic Information

Product Name	2-(1-Methyl-1H-Pyrazol-3-Yl)-Pyridine-5-Boronic Acid Pinacol Ester
CAS No.	1319258-04-2
Molecular Formula	C15H20BN3O2
Molecular Weight	285.15 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(1-methyl-1H-pyrazol-3-yl)pyridine; 2-(1-Methyl-1H-pyrazol-3-yl)pyridine-5-boronic acid pinacol ester; 2-(1-Methyl-1H-pyrazol-3-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-(1-Methyl-1H-pyrazol-3-yl)pyridin-5-ylboronic acid pinacol ester; 1319258-04-2; Pyridine, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(1-methyl-1H-pyrazol-3-yl)-
EINECS	Contact for details

Quality Control

Our 2-(1-Methyl-1H-Pyrazol-3-Yl)-Pyridine-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and support your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.