Description

2-Phenyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyrimidine is a high-value, synthetically versatile boronic ester derivative, serving as a critical building block in modern organic synthesis. Its core value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and organic electronic materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex heterocyclic compounds for oncology, antiviral, and central nervous system (CNS) drug candidates.
• Agrochemical Research: Building block for creating novel pesticides, herbicides, and fungicides with improved efficacy and selectivity.
• Material Science: Used in the development of organic light-emitting diodes (OLEDs), semiconductors, and conductive polymers.
• Chemical Biology: Employed in the synthesis of molecular probes and bioconjugates for target identification and validation.
• Academic & R&D: Fundamental reagent in university and industrial research laboratories for methodological development and library synthesis.
• Scale-up Process Chemistry: Suitable for process optimization and pilot-scale production due to its stability and reactivity profile.

Basic Information

Product Name	2-Phenyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyrimidine
CAS No.	1319255-85-0
Molecular Formula	C16H19BN2O2
Molecular Weight	282.15 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-phenylpyrimidine; 2-Phenyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine; 2-Phenylpyrimidine-5-boronic acid pinacol ester; Pyrimidine-5-boronic acid, 2-phenyl-, 1,1-dimethylethyl ester; (2-Phenylpyrimidin-5-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 2-Phenyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyrimidine is manufactured under strict quality management systems. We guarantee high purity and consistency, with standard specifications typically meeting or exceeding 97% purity (HPLC). Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability and prevent hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.