Description

2-Amino-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde is a high-value, multi-functional organic building block that combines an aldehyde group, an aromatic amine, and a pinacol boronate ester in a single molecule. This unique structure makes it a critical intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl systems. It is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and advanced materials science who require precise molecular architecture.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially those containing biaryl motifs common in kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aromatic coupling.
• Material Science Precursor: Serves as a monomer or linker for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel bidentate ligands and organometallic catalysts.
• Chemical Biology Probes: Utilized to create tagged molecules and bioconjugates for proteomics and diagnostic assay development.
• Academic and R&D: A versatile reagent for methodological development in organic synthesis and medicinal chemistry research.

Basic Information

Item	Detail
Product Name	2-Amino-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde
CAS No.	1319197-32-4
Molecular Formula	C13H18BNO3
Molecular Weight	247.10 g/mol
Synonyms	5-Formyl-2-aminophenylboronic acid pinacol ester; 2-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde; (2-Amino-5-formylphenyl)boronic acid pinacol ester; 5-Aldehyde-2-aminophenylboronic acid pinacol ester; 2-Amino-5-borono-benzaldehyde pinacol ester; PINACA aldehyde precursor; AATB
EINECS	Contact for details

Quality Control

Every batch of our 2-Amino-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde is produced and tested under a strict quality management system. We ensure high purity and lot-to-lot consistency through advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to light and oxidation, prolonged exposure to air and ambient light should be avoided. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.