Description

2,6-Difluoro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline is a high-value, multi-functional boronic ester derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its primary commercial value lies in enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable building blocks for drug discovery, active ingredient synthesis, and functional polymer development.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially in the development of fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the difluoroaniline and boronate groups impart specific biological activity and metabolic stability.
• Material Science: Serves as a monomer or precursor in the synthesis of advanced polymers, liquid crystals, and organic electronic materials (OLEDs, OFETs) requiring precise fluorine substitution.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for methodology development, library synthesis, and exploring new chemical spaces via palladium-catalyzed cross-coupling.
• Bioconjugation & Probe Development: Utilized in the synthesis of molecular probes, imaging agents, and bioconjugates where the amine group allows for further functionalization with targeting molecules.

Basic Information

Product Name	2,6-Difluoro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline
CAS No.	1315692-91-1
Molecular Formula	C12H16BF2NO2
Molecular Weight	255.07 g/mol
Synonyms	3-Amino-2,6-difluorophenylboronic acid pinacol ester; 2,6-Difluoro-3-aminophenylboronic acid pinacol ester; (3-Amino-2,6-difluorophenyl)boronic acid pinacol ester; 2,6-Difluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,6-difluoroaniline; 1315692-91-1; 2,6-Difluoro-3-aminophenylBPin
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profiles, and physical data. Our quality commitment ensures material consistency and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (nitrogen or argon) when possible to maintain stability. For long-term storage, keep at 2-8°C. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.